{"id":59215,"date":"2021-09-01T08:26:00","date_gmt":"2021-09-01T06:26:00","guid":{"rendered":"https:\/\/www.donat.com\/?p=59215"},"modified":"2022-06-09T14:00:39","modified_gmt":"2022-06-09T12:00:39","slug":"pravilna-prebava-in-crevesna-mikrobiota","status":"publish","type":"post","link":"https:\/\/www.donat.com\/sl\/pravilna-prebava-in-crevesna-mikrobiota\/","title":{"rendered":"Pravilna prebava in \u010drevesna mikrobiota"},"content":{"rendered":"\n

Gastrointestinalni trakt omogo\u010da medsebojno delovanje \u010dlovekovega organizma in zunanjega okolja. Pri tem ima zelo pomembno vlogo bariera \u010drevesne sluznice, na njeno delovanje pa vplivajo motnje prebavnih procesov, absorpcije in presnove. \u010crevesna bariera usklajuje fiziolo\u0161ke procese, ki omogo\u010dajo normalno homeostazo. V \u010drevesni svetlini delujejo razli\u010dni okoljski dejavniki, ki vplivajo na mikrobioto.[1] Lokacija in gostota mikroorganizmov v prebavnem traktu sta razli\u010dni tako v podol\u017eni (od ustne votline do danke) kot pre\u010dni smeri (od epitelija do svetline). Na razli\u010dno sestavo in gostoto poselitve mikrobov vplivajo pH, koncentracija \u017eol\u010da, dostopnost hranilnih snovi, usklajeno delovanje imunskega sistema idr.[2] Najve\u010dja gostota poselitve bakterij je v debelem \u010drevesu, in sicer od 1011 do 1012 bakterij na gram, tj. 60 % celotne mase blata.[3] Voda se izlo\u010da po vsem gastrointestinalnem traktu od dvanajstnika do spodnjega dela debelega \u010drevesa. Epitelij mora biti hidriran, da deluje pravilno.<\/p>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

\u010ce sestava mikrobiote gastrointestinalnega trakta ni pravilna, lahko signalni sistem osi mikrobiota\u2013\u010drevesje\u2013mo\u017egani neha pravilno delovati, zato se spremeni gibanje \u010drevesja.[4,5] Tudi kon\u010dni produkti bakterijske fermentacije lahko u\u010dinkujejo na gibanje \u010drevesja. Ugotovili so, da na gibanje \u010drevesja prav tako vpliva imunski sistem, saj se pojavljajo novi dokazi o vnetni reakciji pri nekaterih bolnikih z zaprtostjo. Zato je izjemno pomembno zagotoviti pravilno prebavo pri bolnikih z motnjami \u010drevesnega mikrobioma ter tako vplivati na kakovost in koli\u010dino sestave \u010drevesja.<\/p>\n\n\n\n

V raziskavah (Bothe G., Coh A., Auinger A., 2015, Indejkina L. H., 2018) so pokazali, da zdravilna mineralna voda Donat vpliva na delovanje gastrointestinalnega trakta.[6,7] V raziskavah so statisti\u010dno pomembno pokazali, da u\u017eivanje 200 ml zdravilne mineralne vode trikrat na dan v obdobju treh tednov skraj\u0161a \u010das prenosa vsebine \u010drevesja in normalizira pogostost iztrebljanja. Donat deluje kot osmotsko odvajalo in omogo\u010da brezhibno delovanje \u017eol\u010dnega mehurja ter tako spodbuja izlo\u010danje \u017eol\u010dnih kislin in delovanje trebu\u0161ne slinavke ter vpliva na nastajanje encimov.<\/p>\n\n\n\n

U\u017eivanje zdravilne mineralne vode Donat (Slovenija, Roga\u0161ka Slatina) je zato mogo\u010de priporo\u010diti pri motnjah rednega praznjenja \u010drevesja, saj lahko omogo\u010di udoben obstoj mikrobne skupnosti v \u010drevesju.<\/p>\n\n\n

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\"Plastenka<\/figure>\n<\/div>\n\n\n

Seznam literature<\/h3>\n\n\n\n
  1. Zhu H., Hart C.A., Sales D., Roberts N.B. \u0411\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0435 \u0443\u0431\u0438\u0439\u0441\u0442\u0432\u043e \u0432 \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043d\u043e\u043c \u0441\u043e\u043a\u0435 \u2013 \u0432\u043b\u0438\u044f\u043d\u0438\u0435 \u0440\u041d \u0438 \u043f\u0435\u043f\u0441\u0438\u043d\u0430 \u043d\u0430 Escherichia coli \u0438 Helicobacter pylori. J. Med. \u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043b., 2006, I. 55, P. 1265\u20131270.<\/li>
  2. Tropini C., Earle K.A., Huang K.C., Sonnenburg J.L. \u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430: \u043f\u043e\u0434\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u0435 \u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0430\u0446\u0438\u0438 \u043a \u0444\u0443\u043d\u043a\u0446\u0438\u0438. Cell Host Microbe, 2017, I. 21, P. 433\u2013442.<\/li>
  3. Sekirov I.,Russell S.L., Antunes L.C., Finlay B.B. \u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u0430 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u0432 \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u0435 \u0438 \u0431\u043e\u043b\u0435\u0437\u043d\u0438. \u0424\u0438\u0437\u0438\u043e\u043b. REV., 2010, I. 90, P. 859\u2013904.<\/li>
  4. Kennedy P.J., Clarke G., Quigley E.M., Groeger J.A., Dinan T.G., Cryan J.F. Gut memories: towards a cognitive neurobiology of irritable bowel syndrome. Neurosci Biobehav Rev. 2012, I. 36, P. 310\u2013340.<\/li>
  5. Carabotti M., Scirocco A., Maselli M.A., Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol., 2015, I. 28, P. 203\u2013209.<\/li>
  6. Bothe G., Coh A., Auinger A. Efficacy and safety of a natural mineral water rich in magnesium and sulphate for bowel function: a double-blind, randomized, placebocontrolled study. Eur J Nutr 2015. (https:\/\/link.springer.com\/article\/10.1007\/s00394-015-1094-8)<\/li>
  7. \u0418\u043d\u0434\u0435\u0439\u043a\u0438\u043d\u0430 \u041b.\u0425. \u041e\u0446\u0435\u043d\u043a\u0430 \u0432\u043b\u0438\u044f\u043d\u0438\u044f \u043b\u0435\u0447\u0435\u0431\u043d\u043e\u0439 \u043c\u0438\u043d\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0439 \u0432\u043e\u0434\u044b \u0414\u043e\u043d\u0430\u0442 \u041c\u0430\u0433\u043d\u0438\u044f (Donat) \u043d\u0430 \u043c\u043e\u0442\u043e\u0440\u043d\u043e-\u044d\u0432\u0430\u043a\u0443\u0430\u0442\u043e\u0440\u043d\u0443\u044e \u0444\u0443\u043d\u043a\u0446\u0438\u044e \u0442\u043e\u043b\u0441\u0442\u043e\u0439 \u043a\u0438\u0448\u043a\u0438 \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u043c\u0438 \u0437\u0430\u043f\u043e\u0440\u0430\u043c\u0438 \/ \u041b.\u0425. \u0418\u043d\u0434\u0435\u0439\u043a\u0438\u043d\u0430, \u0415.\u0421. \u0421\u043e\u043a\u043e\u043b\u043e\u0432\u0430, \u041d.\u0413. \u0421\u0430\u043c\u0441\u043e\u043d\u043e\u0432\u0430, \u0410.\u0418. \u041f\u0430\u0440\u0444\u0435\u043d\u043e\u0432 \/\/ \u0414\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u0430\u044f \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u043d\u0442\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u044f. \u2013 \u21161. \u2013 2018. \u2013 \u0421. 59-60. (https:\/\/doi.org\/10.17116\/dokgastro20187155-110)<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"

    Gastrointestinalni trakt omogo\u010da medsebojno delovanje \u010dlovekovega organizma in zunanjega okolja. Pri tem ima zelo pomembno vlogo bariera \u010drevesne sluznice, na njeno delovanje pa vplivajo motnje prebavnih procesov, absorpcije in presnove. \u010crevesna bariera usklajuje fiziolo\u0161ke procese, ki omogo\u010dajo normalno homeostazo. V \u010drevesni svetlini delujejo razli\u010dni okoljski dejavniki, ki vplivajo na mikrobioto.[1] Lokacija in gostota mikroorganizmov v …<\/a><\/p>\n","protected":false},"author":5,"featured_media":95867,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[147],"tags":[],"class_list":["post-59215","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-strokovni-clanki"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/posts\/59215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/comments?post=59215"}],"version-history":[{"count":5,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/posts\/59215\/revisions"}],"predecessor-version":[{"id":95874,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/posts\/59215\/revisions\/95874"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/media\/95867"}],"wp:attachment":[{"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/media?parent=59215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/categories?post=59215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.donat.com\/sl\/wp-json\/wp\/v2\/tags?post=59215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}